Publications
20. Troup, R. I., Fallan, C., Baud, M. G. J.
Current strategies for the design of PROTAC linkers: a critical
review.
Exploration of Targeted Anti-tumor Therapy, 1, 273-312, (2020).
DOI: 10.37349/etat.2020.00018
19. Chasov, V., Mirgayazova, R., Zmievskaya, E., Khadiullina, R.,
Valiullina, A., Stephenson Clarke, J., Rizvanov, A., Baud, M.,
Bulatov, E.
Key Players in the Mutant p53 Team: Small Molecules, Gene
Editing, Immunotherapy
Frontiers in Oncology, 10, 1460, (2020).
DOI: 10.3389/fonc.2020.01460
18. Baud, M. G. J., Bauer, M. R., Verduci, L., Dingler, F. A., Patel,
K. J., Horil Roy, D., ... Fersht, A. R.
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines.
European Journal of Medicinal Chemistry, 152, 101-114, (2018).
DOI: 10.1016/j.ejmech.2018.04.035
17. Runcie, A. C., Zengerle, M., Chan, K-H., Testa, A., van
Beurden, L., Baud, M. G. J., ... Ciulli, A.
Optimization of a “bump-and-hole” approach to allele-selective
BET bromodomain inhibition.
Chemical Science, (2018).
DOI: 10.1039/C7SC02536J
16. Khan, R., Marsh, G., Felix, R., Kemmitt, P. D., Baud, M. G. J.,
Ciulli, A., & Spencer, J.
Gram scale laboratory synthesis of TC AC 28, a high affinity BET bromodomain ligand.
ACS Omega, 2(8), 4328-4332, (2017).
DOI: 10.1021/acsomega.7b00780
15. Weston, C. E., Krämer, A., Colin, F., Yildiz, Ö., Baud, M. G. J.,
Meyer-Almes, F-J., & Fuchter, M. J.
Toward photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors.
ACS Infectious Diseases, 3(2), 152-161, (2017).
DOI: 10.1021/acsinfecdis.6b00148
14. Bauer, M. R., Jones, R. N., Baud, M., Wilcken, R., Boeckler, F.
M., Fersht, A. R., ... Spencer, J.
Harnessing fluorine–sulfur contacts and multipolar interactions for the design of p53 mutant Y220C rescue drugs.
ACS Chemical Biology, 11(8), 2265-2274, (2016).
DOI: 10.1021/acschembio.6b00315
13. Baud, M., Lin-Shiao, E., Zengerle, M., Tallant, C., & Ciulli, A.
New synthetic routes to triazolo-benzodiazepine analogues: expanding the scope of the bump-and-hole approach for selective bromo and extra-terminal (bet) bromodomain inhibition.
Journal of Medicinal Chemistry, 59(4), 1492-1500, (2016).
DOI: 10.1021/acs.jmedchem.5b01135
12. Richardson, R. D., Baud, M., Weston, C. E., Rzepa, H. S.,
Kuimova, M. K., & Fuchter, M. J.
Dual wavelength asymmetric photochemical synthesis with circularly polarized light.
Chemical Science, 6(7), 3853-3862, (2015).
DOI: 10.1039/C4SC03897E


11. Joerger, A. C., Bauer, M. R., Wilcken, R., Baud, M., Harbrecht,
H., Exner, T. E., ... Fersht, A. R.
Exploiting transient protein states for the design of small-molecule stabilizers of mutant p53.
Structure, 23(12), 2246-2255, (2015).
10. Baud, M. G. J., Lin-Shiao, E., Cardote, T., Tallant, C.,
Pschibul, A., Chan, K-H., ... Ciulli, A.
A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes.
Science, 346(6209), 638-641, (2014).
9. Meyners, C., Baud, M., Fuchter, M. J., & Meyer-Almes, F-J.
Analytical Biochemistry, 460, 39-46, (2014).
8. Dias, D. M., Van Molle, I., Baud, M., Galdeano, C.,
Geraldes, C. F. G. C., & Ciulli, A. Letter.
Is NMR fragment screening fine-tuned to assess druggability of protein–protein interactions?
ACS Medicinal Chemistry Letters, 5(1), 23-28, (2014).
DOI: 10.1021/ml400296c
7. Meyners, C., Baud, M., Fuchter, M. J., & Meyer-Almes, F-J.
Journal of Molecular Recognition, 27(3), 160-172, (2014).
DOI: 10.1002/jmr.2345
6. Baud, M., Leiser, T., Petrucci, V., Gunaratnam, M.,
Neidle, S., Meyer-Almes, F-J., & Fuchter, M. J.
Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors.
Beilstein Journal of Organic Chemistry, 9, 81-88, (2013).
DOI: 10.3762/bjoc.9.11
5. Baud, M., Leiser, T., Haus, P., Samlal, S., Wong, A. C.,
Wood, R. J., Fuchter, M. J.
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets.
Journal of Medicinal Chemistry, 55(4), 1731-1750, (2012).
DOI: 10.1021/jm2016182
4. Baud, M., Haus, P., Leiser, T., Meyer-Almes, F-J., &
Fuchter, M. J.
ChemMedChem, 8(1), 149-156, (2012).
3. Baud, M., Leiser, T., Meyer-Almes, F-J., & Fuchter, M. J.
New synthetic strategies towards psammaplin A, access
to natural product analogues for biological evaluation.
Organic & Biomolecular Chemistry, 9(3), 659-662, (2011).
DOI: 10.1039/C0OB00824A
2. Borcard, F., Baud, M., Bello, C., Dal Bello, G., Grossi, F.,
Pronzato, P., ... Vogel, P.
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity.
Bioorganic & Medicinal Chemistry Letters, 20(17), 5353-5356, (2010).
1. Chauvin, A-S., Comby, S., Baud, M., De Piano, C., Duhot,
C., & Bünzli, J-C. G.
Inorganic Chemistry, 48(22), 10687-10696, (2009).
DOI: 10.1021/ic901424w